Navigating RNA sequencing (RNA-seq): considerations and challenges
RNA sequencing (RNA-seq) has become immensely popular and indispensable in modern biological research. We look at the considerations and challenges of this technology.
Integrate multiple modes of biology from a single sample in a single experiment to provide transformative insights into health and disease.
Current technologies are unable to reliably resolve both genetic and epigenetic sequences at low sample input and miss important information. biomodal’s duet multiomics solution evoC gives you access to the 6-base genome – all 4 canonical bases and distinguishes 5‑methylcytosine (5mC) and 5‑hydroxymethylcytosine (5hmC) – from a single 5ng DNA sample, in a single experiment, with high accuracy.
Combined epigenetic and genetic analysis in a single sequencing run lets you access the most critical information from your DNA samples.
Better characterise liquid biopsy and genomic DNA samples of early stage cancer for diagnostic and therapy development.
Combined data reveals the role of methylation in neurodegeneration.
Pinpoint epigenetic changes that determine patterns of disease and health throughout a lifespan.
Detect minute epigenetic changes to better understand maternal and foetal health.
Improved DNA-based diagnostics with the ability to see disease-relevant changes from low input samples
A true 6-base genome that distinguishes 5mC and 5hmC together with all four canonical bases to measure multiple modes of biology
Assess all four canonical bases plus modified cytosine
RNA sequencing (RNA-seq) has become immensely popular and indispensable in modern biological research. We look at the considerations and challenges of this technology.
Novel solution – duet evoC – distinguishes 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) revealing unprecedented insights into current and future states of disease using one 5ng DNA sample
Epigenetics, a captivating field of study, has revolutionised our understanding of gene regulation.
We can help you reveal new data and multimodal insights from your research.